About ProMetic

 

ProMetic Life Sciences Inc. is a long established publicly traded (TSX symbol: PLI, OTCQX: PFSCF), biopharmaceutical corporation with a globally recognized expertise in bioseparations, plasma-derived therapeutics and small-molecule drug development. ProMetic offers its state of the art technologies for large-scale purification of biologics, drug development, proteomics and the elimination of pathogens to a growing base of industry leaders and uses its own affinity technology that provides for highly efficient extraction and purification of therapeutic proteins from human plasma in order to develop best-in-class therapeutics. ProMetic is also active in developing its own novel therapeutics products targeting unmet medical needs in the field of fibrosis, anemia, neutropenia, cancer, and autoimmune disease/inflammation as well as certain nephropathies.  ProMetic’s business is organized into two distinct operating segments; Protein Technologies and Therapeutics, supported by a Head Office in Laval, Canada, R&D facilities in the UK, the USA and Canada as well as manufacturing facilities in the UK and business development activities in the USA, Europe and Asia.

 

Therapeutics

Orally active PBI-1402 Hematology – New Chemical Entities (NCEs) Oncology – New Chemical Entities (NCEs)

Advancing in clinical trials for the treatment of anemia:

  • Chemotherapy-induced anemia
  • Cancer related anemia
  • Anemia associated with Chronic Kidney Disease
  • Proprietary additions to PBI-1402
  • Confirmed erythropoietic activity in vivo
    PBI-4050
    PBI-4265
    PBI-4283
    PBI-4299
  • Promising new lead compounds for the treatment of neutropenia
  • Confirmed anti-cancer activity in vivo
  • Most compounds orally active
  • Could allow for lower doses of chemotherapy, resulting in less side effects like anemia / neutropenia
    PBI-0110
    PBI-1393
    PBI-1522
    PBI-1668
    PBI-1737

Protein Technologies

Prion Capture Technology Bioseparation Products Human Plasma-derived Therapeutics
  • P-Capt® filters to remove infectious prions from blood and blood components
  • Prion capture affinity resin scaled-up for industrial process to remove prions from plasma-derived products
  • To enhance detection of “mad cow disease” in cattle and vCJD in humans
  • Mimetic Ligand™ for large-scale manufacturing
  • Mabsorbents® ligands targeting the purification of MAbs and Fabs
  • Fabsorbent™ for antibody fragment purification
  • Other Affinity Adsorbents
  • Hyperimmune Hepatitis B
  • Hyperimmune CMV
  • Plasminogen, Factor VIII
  • Rare bleeding disorders
  • Fibrinogen
  • VIG, Alpha-1 antitrypsin
  • Other proteins targeted for rare disorders (Orphan Drugs)